| 车站 | 到达 | 发车 | 走行 | 里程 | |
| 1 | 郑州东 | 09:46 | 09:46 | 00:00 | - |
| 2 | 西华 | 10:34 | 10:36 | 00:48 | - |
| 3 | 周口东 | 10:45 | 10:47 | 00:57 | - |
| 4 | 界首南 | 11:08 | 11:10 | 01:18 | - |
| 5 | 临泉 | 11:20 | 11:22 | 01:28 | - |
| 6 | 阜阳西 | 11:36 | 11:40 | 01:42 | - |
| 7 | 淮南南 | 12:14 | 12:16 | 02:16 | - |
| 8 | 合肥北城 | 12:35 | 12:37 | 02:35 | - |
| 9 | 合肥 | 12:50 | 12:54 | 02:48 | - |
| 10 | 南京南 | 13:50 | 13:50 | 03:44 | 371 |